Season 6

Richard Lewis

January 9, 2001

Vitamin C

January 10, 2001

Julia Stiles

January 11, 2001

William Dafoe

January 15, 2001

Tim Robbins

January 16, 2001

Sam Donaldson

January 17, 2001

Lynn Whitfield

January 18, 2001

Bill O'Reilly

January 22, 2001

Matthew McConaughey

January 23, 2001

Terry Bradshaw

January 24, 2001

Topher Grace

January 25, 2001

David Boreanaz

January 29, 2001

Dyan Cannon

January 30, 2001

James van der Beek

January 31, 2001

Tim Blake Nelson

February 1, 2001

Dave Grohl

February 12, 2001

Kermit the Frog

February 13, 2001

Jessica Alba

February 14, 2001

Wanda Sykes

February 15, 2001

Greg Germann

February 20, 2001

Chris Rock

February 21, 2001

Kelly Ripa

February 22, 2001

Ted Danson

February 26, 2001

Joe Pantoliano

February 27, 2001

Heather Locklear

February 28, 2001

Warren Christopher

March 1, 2001

Martin Short

March 5, 2001

Ed Burns

March 6, 2001

Carmen Electra

March 7, 2001

Javier Bardem

March 8, 2001

Chris Meloni

March 19, 2001

Mary Stuart Masterson

March 20, 2001

Jeff Varner

March 21, 2001

Denis Leary

March 22, 2001

Richard Roeper

March 26, 2001

Richard Lewis

March 27, 2001

Mark Harmon

March 28, 2001

Jennifer Love Hewitt

March 29, 2001

Lisa Ling

April 2, 2001

Amy Sedaris

April 3, 2001

D.L. Hughley

April 4, 2001

Steven Weber

April 5, 2001

Paul Reubens

April 9, 2001

Bob Costas

April 10, 2001

Damon Wayans

April 11, 2001

Brittany Daniel

April 12, 2001

Don Hewitt

April 23, 2001

Rachael Leigh Cook

April 24, 2001

Tom Green

April 25, 2001

Tom Cavanagh

April 26, 2001

Eric McCormack

April 30, 2001

Dominic Chianese

May 1, 2001

No Guest

May 2, 2001

Robert Patrick

May 3, 2001

Chris Robinson

May 7, 2001

James Van Der Beek

May 8, 2001

Richie Sambora

May 9, 2001

Patricia Richardson

May 10, 2001

Maura Tierney

May 14, 2001

Denise Quiñones

May 15, 2001

Heath Ledger

May 16, 2001

Jerry Springer

May 17, 2001

Richard Schiff

May 29, 2001

Bradley Whitford

May 30, 2001

Leah Remini

May 31, 2001

Jake Johannsen

June 4, 2001

Richard Belzer

June 5, 2001

Al Roker

June 6, 2001

Bernie Mac

June 7, 2001

Joe Queenan

June 11, 2001

Gene Simmons

June 12, 2001

David Duchovny

June 13, 2001

Jeff Greenfield

June 14, 2001

Martin Short

June 18, 2001

Michael Rapaport

June 19, 2001

Alec Baldwin

June 20, 2001

Mýa

June 21, 2001

Sam Robards

June 25, 2001

Johnny Knoxville

June 26, 2001

Jet Li

June 27, 2001

Bridget Fonda

June 28, 2001

Sean Hayes

July 9, 2001

451. Sean Hayes First aired: 7/9/2001 Production Code: 6001 Tonight, actor Sean Hayes from Will & Grace.

The Spice Girls

July 10, 2001

452. Spice Girls First aired: 7/10/2001 Production Code: 6002 Tonight, the Spice Girls. Replay of Posh & Baby Spice Interview from (2000-10-25).

James Woods

July 11, 2001

Vince Vaughn

July 12, 2001

Jon Favreau

July 16, 2001

Maria Bartiromo

July 17, 2001

Ed Norton

July 18, 2001

Hank Azaria

July 19, 2001

Larry Miller

July 23, 2001

Paul Giametti

July 24, 2001

Senator Joe Lieberman

July 25, 2001

Senator John McCain

July 26, 2001

Jerri Manthey

July 30, 2001

Peter Krause

July 31, 2001

Jackie Chan

August 1, 2001

Janeane Garofalo

August 2, 2001

Andie MacDowell

August 6, 2001

Joe Rogan

August 7, 2001

Tara Reid

August 8, 2001

Jason Biggs

August 9, 2001

David Rakoff

August 13, 2001

John Carpenter

August 14, 2001

Seth Green

August 15, 2001

Fabio

August 16, 2001

Cuba Gooding Jr.

August 20, 2001

Griffin Dunne

August 21, 2001

Will Ferrell

August 22, 2001

Kevin Smith

August 23, 2001

They Might Be Giants

September 10, 2001

Dave Navarro

September 20, 2001 - The Comeback episode

September 20, 2001

The Daily Show returns to the air from the New York studio in their first episode after the tragedy of September 11th, 2001.

Frank Rich

September 24, 2001

Aaron Brown

September 25, 2001

Jeff Greenfield

September 26, 2001

Tenacious D

September 27, 2001

Kelsey Grammer

October 1, 2001

Jim Belushi

October 2, 2001

Stephen Morse

October 3, 2001

Kate Beckinsale

October 4, 2001

Owen Wilson

October 9, 2001

Jeremy Piven

October 10, 2001

John Miller

October 11, 2001

Emeril Lagasse

October 15, 2001

Lorraine Bracco

October 16, 2001

Tonight, actress Lorraine Bracco from The Sopranos.

Snoop Dogg

October 17, 2001

Fareed Zakaria

October 18, 2001

Lance Bass

October 22, 2001

Don Dahler

October 23, 2001

Greta Van Susteren

October 24, 2001

Jeff Bridges

October 25, 2001

Rob Morrow

October 30, 2001

Richard Holbrooke

October 31, 2001

Kevin Spacey

November 1, 2001

Paul Rudd

November 5, 2001

Tonight, actor Paul Rudd.

P.J. O'Rourke

November 6, 2001

George Stephanopoulos

November 7, 2001

Jennifer Saunders

November 8, 2001

Steve Kroft

November 12, 2001

Anne Robinson

November 13, 2001

Carson Daly

November 14, 2001

John Stamos

November 15, 2001

Edward Burns

November 26, 2001

Star Jones

November 27, 2001

Jennifer Garner

November 28, 2001

David Halberstam

November 29, 2001

Nadine Strossen

December 3, 2001

John Edward

December 4, 2001

Marg Helgenberger

December 5, 2001

Ted Danson

December 6, 2001

Stephen Colbert as Al Sharpton

December 10, 2001

Dave Gorman

December 11, 2001

Janeane Garofalo

December 12, 2001

Tracey Ullman

December 13, 2001

Elijah Wood

December 17, 2001

Peggy Noonan

December 18, 2001

Gary Sinise

December 19, 2001

Jamie Foxx

December 20, 2001