Season 22

Luke Wilson, Julie Chen, Lee Brice

September 2, 2014

Kristen Wiig, Sen. Elizabeth Warren, The New Pornographers

September 3, 2014

Steve Buscemi, Indy Car Season Champ, Alt-J

September 4, 2014

Tina Fey, Moody McCarthy, Kevin Drew

September 5, 2014

Bill Maher, Henrik Lundqvist, Spoon

September 8, 2014

Michael Strahan, Richard Branson, Interpol

September 9, 2014

Dr. Phil, Katharine McPhee, Death from Above 1979, Ray Benson

September 10, 2014

Jason Bateman, Billy Eichner, Ryan Adams

September 11, 2014

Mindy Kaling, Jake Johannsen, Maddie & Tae

September 12, 2014

Mark Harmon, "Jungle" Jack Hanna

September 22, 2014

Denzel Washington, Lenny Kravitz

September 23, 2014

Kelly Ripa, Jim Gaffigan, Paloma Faith

September 24, 2014

Jerry Seinfeld, Michael Jackson ONE

September 25, 2014

Ted Danson, Andrew Norelli

September 26, 2014

Neil Patrick Harris, Jamie Oliver, Aretha Franklin

September 29, 2014

John Oliver, Maggie Q, Bleachers

September 30, 2014

Bill O'Reilly, Cristin Milioti

October 1, 2014

Johnny Galecki, Andre Benjamin, Delta Spirit

October 2, 2014

Mariska Hargitay, Simon Amstell, Kandace Springs

October 3, 2014

Aziz Ansari, Tom Dreesen

October 6, 2014

Robert Downey Jr., Sarah Paulson, Lizzo

October 7, 2014

Anderson Cooper, Gina Rodriguez, Hatsune Miku

October 8, 2014

Robert Duvall, Elle Fanning, Rival Sons

October 9, 2014

Chelsea Handler; Keegan-Michael Key and Jordan Peele; Angaleena Presley

October 10, 2014

TV host Chelsea Handler; comics Keegan-Michael Key and Jordan Peele; Angaleena Presley performs.

Russell Brand, Dave Grohl, Foo Fighters

October 13, 2014

Michael Keaton, Foo Fighters

October 14, 2014

Bill Murray, Foo Fighters

October 15, 2014

Tom Selleck, Jenny Slate, Foo Fighters

October 16, 2014

Jessica Chastain, Lenny Marcus, Foo Fighters

October 17, 2014

Amy Poehler, Sen. Jeff Flake, Sen. Martin Heinrich, Mastodon, Jerry Lee Lewis

October 27, 2014

Taylor Swift, Tom Mison

October 28, 2014

Jim Carrey, David Tennant

October 29, 2014

Brian Williams, Perfume Genius

October 30, 2014

Keith Olbermann, Brian Regan, Run the Jewels

October 31, 2014

Martin Short, Father John Misty

November 3, 2014

Jennifer Lopez, Rob Riggle, Kimbra

November 5, 2014

Whoopi Goldberg, Jimmy Page, Mapei

November 6, 2014

Amy Schumer, Jeff Caldwell

November 7, 2014

Katie Holmes, Alex Zanardi

November 10, 2014

Steve Carell, Martha Stewart, OK Go

November 11, 2014

Jennifer Lawrence, Boris Johnson

November 12, 2014

Jon Stewart, Shawn Mendes

November 13, 2014

Kristin Chenoweth; Chris Young

November 14, 2014

Actress Kristin Chenoweth; Chris Young performs.

Jason Sudeikis, Allison Janney, Damien Rice

November 17, 2014

Stupid Pet Tricks, Charlie Day, Hiss Golden Messenger

November 18, 2014

Regis Philbin, Hundred Waters

November 19, 2014

Edward Norton, Jessye Norman

November 20, 2014

Norman Lear, TV on the Radio

November 21, 2014

Seth Rogen, Amy Sedaris

November 24, 2014

Emily Blunt, Adam Resnick, Wu-Tang Clan

November 25, 2014

Jake Gyllenhaal, Dr. John P. Holdren, Nico & Vinz

November 26, 2014

Joaquin Phoenix, Cristela Alonzo, Al Green

December 8, 2014

Ben Stiller, Olivia Munn, LaLa Brooks

December 9, 2014

Meryl Streep, Rebel Wilson, J. Cole

December 10, 2014

Chris Rock, Sting

December 11, 2014

Jamie Foxx, Robert Klein, Dan Penn

December 12, 2014

Emma Stone Top, Marcus Mariota, Bob Seger

December 15, 2014

New Holiday Toys, Anna Kendrick, Charli XCX

December 16, 2014

Tom Brokaw, Will Nelson & Billy Joe Shaver

December 17, 2014

Rosie O’Donnel,l Jeff Altman

December 18, 2014

Jay Thomas, Josh Brolin, Darlene Love

December 19, 2014

The final Christmas episode. Jay Thomas drops by to once again tell "The best talk show story, ever", then he and David try to knock the meatball off the Christmas tree in the Late Show Quarterback Challenge. An interview with Josh Brolin. The show wraps up with Darlene Love's last Late Show performance of Christmas (Baby Please Come Home).

Kathy Griffin, David Oyelowo, Lera Lynn

January 5, 2015

Ethan Hawke, Allison Williams, Parquet Courts

January 6, 2015

Julianne Moore, Catfish & the Bottlemen

January 7, 2015

Donald Trump, Chelsea Peretti, Foxygen

January 8, 2015

Michael Somerville, Nicole Atkins

January 9, 2015

Gordon Ramsay, Adam Devine, St. Paul and the Broken Bones

January 12, 2015

Anderson Cooper, Shovels & Rope

January 13, 2015

Amanda Peet, Ryn Weaver

January 14, 2015

Larry David, Dan Patrick, Sleater-Kinney

January 15, 2015

Urban Meyer, Johnny Beehner, Ella Henderson

January 16, 2015

Louis CK, Nicolle Wallace, the Lone Bellow

January 26, 2015

Andrew Luck, Oscar Isaac, Drenge

January 27, 2015

Viola Davis, Ben Schwartz, Marty Stuart

January 28, 2015

John Oliver, Mayim Bialik, Death Cab for Cutie

January 29, 2015

Aziz Ansari, Brian Kiley, Ben Howard

January 30, 2015

Jack Hanna, Sharon Jones and the Dap-Kings

February 2, 2015

Dr. Phil McGraw, Robin Tunney, Diana Krall

February 3, 2015

Ryan Reynolds, Dierks Bentley

February 4, 2015

Martin Short, Bettye Lavette

February 5, 2015

Sienna Miller, Andy Kindler, Bob Mould

February 6, 2015

Steve Carell, Dr. Cornel West

February 9, 2015

Courtney Love, Chris Elliott, Rhiannon Giddens

February 10, 2015

Bill Belichick, Elisabeth Moss, Madisen Ward and the Mama Bear

February 11, 2015

Tom Hanks, Sturgill Simpson

February 12, 2015

Bill Hader, Pat McGann, Shakey Graves

February 13, 2015

Matthew Perry, Adam Scott, Kishi Bashi

February 16, 2015

Dakota Johnson, David Tochinskiy, Twin Shadow

February 17, 2015

Will Smith, Grizfolk

February 18, 2015

Don Cheadle, Ilana Glazer & Abbi Jacobson, Mikky Ekko

February 19, 2015

Kid Scientists, Sean Hayes, Judah & the Lion

February 20, 2015

Helen Mirren, the 2015 Daytona 500 winner, Steve Earle

February 23, 2015

Matthew Broderick, Ellie Kemper, JD McPherson

February 24, 2015

Julianna Margulies, Eric Ripert, Glass Animals

February 25, 2015

Kevin Spacey, Lily James, Alabama Shakes

March 9, 2015

Patricia Arquette, Will Butler

March 10, 2015

Kelsey Grammer, Stevie Wonder

March 11, 2015

Lena Dunham, Bobby Cannavale, Andy Kim with Kevin Drew

March 12, 2015

Kevin Bacon, Jimmie Walker, Airborne Toxic Event

March 13, 2015

Shailene Woodley, Dr. Cornel West, Matthew E. White

March 16, 2015

Will Ferrell, Glen Hansard

March 17, 2015

Norm MacDonald, Theo James

March 18, 2015

Ben Stiller, Tove Lo

March 23, 2015

Bill O'Reilly, Aubrey Plaza

March 24, 2015

James Franco, Jake Johannsen, Action Bronson

March 25, 2015

Neil Patrick Harris, Charlie Cox, the Suffers

March 30, 2015

David Duchovny, Josh Gad, Houndmouth

March 31, 2015

Sen. Al Franken, Billy Eichner, David Sanborn

April 1, 2015

Kelly Ripa, Aasif Mandvi, Fat White Family

April 2, 2015

Mike Myers, Nick Griffin, Banks

April 3, 2015

Sarah Jessica Parker, Julie Chen, Asleep at the Wheel

April 13, 2015

Billy Crystal, Chris Russo, Chris Stapleton

April 14, 2015

Michael J. Fox, Iron & Wine, Ben Bridwell

April 15, 2015

Kevin James, Tom Dreesen, Tracy Chapman

April 16, 2015

Alec Baldwin, John Mayer

April 17, 2015

John Travolta, Amy Schumer, the Waterboys

April 20, 2015

Piedmont Bird Callers, Paul Rudd

April 21, 2015

Bruce Willis, Dawes

April 22, 2015

Robert Downey Jr., Chris Russo, Elvis Costello

April 23, 2015

Jerry Seinfeld, Jason Isbell & Amanda Shires

April 24, 2015

Scarlett Johansson, John Mellencamp, Todd Rundgren

April 27, 2015

Michael Keaton, Future Islands

April 28, 2015

Jack Hanna, John Popper

April 29, 2015

First Lady Michelle Obama Hootie and the Blowfish

April 30, 2015

Steve Martin, Emmylou Harris, Rodney Crowell, Amos Lee, Ralph Stanley, Mark O'Connor

May 1, 2015

President Barack Obama, Will Ferrell, the Avett Brothers, Brandi Carlile

May 4, 2015

Reese Witherspoon, Nathan Lane, Mumford & Sons

May 5, 2015

Martin Short, Norah Jones

May 6, 2015

Tina Fey, First Aid Kit

May 7, 2015

Ray Romano, Brian Regan, Dave Matthews Band

May 8, 2015

Howard Stern, Don Rickles

May 11, 2015

Bill Clinton, Adam Sandler

May 12, 2015

Julia Roberts, Paul Shaffer, Ryan Adams

May 13, 2015

Al Pacino, George Clooney, Tom Waits

May 14, 2015

Oprah Winfrey, Norm Macdonald

May 15, 2015

Tom Hanks, Eddie Vedder

May 18, 2015

Bill Murray, Bob Dylan

May 19, 2015

The Final Late Show with David Letterman

May 20, 2015

6,028th broadcast

Episode 149

May 20, 2015

The final episode includes surprises, memorable highlights and the last Top Ten List.